D5NM (Normosol-M) IV Fluid

Description

Dextrose 5% in Normosol M Solution (D5NM) is a hypertonic solution that is nonpyrogenic and is a nutrient replenisher.

Type of Solution

• Dextrose 5% in Normosol M Solution
• Hypertonic solution of balanced maintenance electrolytes and 5% dextrose injection in water for injection

Classification

• Hypertonic
• Nonpyrogenic
• Parenteral fluid
• Electrolyte
• Nutrient replenisher

Contents

• Each 1000 mL contains 5g of Dextrose Monohydrate,
• 234 mg of sodium chloride
• 128 mg of potassium acetate tetrahydrate and
• 30mg (approximately 1.6 mmol/L) of sodium Metabisulfate.

Mechanism of Action

• When administered intravenously, Normosol-M and 5% Dextrose Injection provides water and electrolytes (with dextrose as a readily available source of carbohydrate) for maintenance of daily fluid and electrolyte requirements, plus minimal carbohydrate calories.
• The electrolyte composition approaches that of the principal ions of normal plasma (extracellular fluid).
• The electrolyte concentration is hypotonic (112 mOsmol/liter) in relation to the extracellular fluid (280 mOsmol/liter).
• One liter provides approximately one-third of the average adult daily requirement for water and principal electrolytes in balanced proportions, with acetate as a bircarbonate alternate,plus 170 calories from dextrose.

Indications of D5NM

• D5NM is indicated for parenteral maintenance of routine daily fluid and electrolyte requirements with minimal carbohydrate calories from dextrose.
• Magnesium in the formula may help to prevent iatrogenic magnesium deficiency in patients receiving prolonged parenteral therapy.

Contraindications

• Hypersensitivity to any of the components.

Dosage

• D5NM is supplied in single-dose 500 and 1000 mL flexible plastic containers.
• 1000 mL @ 30 gtts/min.

Nursing Responsibilities

• Do not administer unless solution is clear and container is undamaged.
• Caution must be exercised in the administration of parenteral fluids, especially those containing sodium ions to patients receiving corticosteroids or corticotrophin.
• Solution containing acetate should be used with caution as excess administration may result in metabolic alkalosis.
• Solution containing dextrose should be used with caution in patients with known subclinical or overt diabetes mellitus.
• Discard unused portion.
• In very low birth weight infants, excessive or rapid administration of dextrose injection may result in increased serum osmolality and possible intracerebral hemorrhage.
• Properly label the IV Fluid
• Observe aseptic technique when changing IV fluid

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